Mitochondrial Signals

MOTS-c is a unique peptide encoded in the DNA of mitochondria, not the nucleus. It acts as an exercise mimetic, improving insulin sensitivity and preventing diet-induced obesity by regulating metabolic homeostasis.

AOD-9604 is a fragment of the HGH molecule (amino acids 177-191). This fragment retains the fat-burning properties of HGH without the growth-promoting or insulin-resistance effects. It specifically targets adipose tissue to release stored fat for energy.

Scientific References

  • Lee C, et al. “The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis…” Cell Metabolism. 2015.
  • Heffernan M, et al. “The effects of human GH fragment 177-191 on lipid metabolism…” Diabetes, Obesity and Metabolism. 2001.